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Pathogenesis and diagnosis of type I allergy
In type I allergy, allergen-specific IgE antibodies are formed upon initial (symptomless) contact. These bind to the surface of mast cells (histamine-rich cells that are present in all mucous membranes). The reaction occurs on second contact within seconds to a few minutes. In the case of allergies, antigens are free/dissolved molecules that are incorrectly viewed as threatening by the immune system. The binding of the antigen (allergen) leads to the activation of the mast cells and basophils and their degranulation through cross-linking of two or more IgE antibodies. Preformed inflammatory mediators such as histamine are immediately released, and later newly synthesized factors such as leukotrienes and prostaglandins are released. While histamine is primarily responsible for the immediate symptoms (watering of the eyes, runny nose, itching, bronchospasm, anaphylaxis), the leukotrienes and prostaglandins initiate the inflammatory reaction and thus the delayed and often chronic symptoms (eczema, asthma, nasal congestion).
100,00 € 50,00 €
Mineralstoffpr­ofil 11+6
20,00 € 10,00 €
Übersetzungen
20,00 € 10,00 €
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20,00 € 10,00 €
ALEX IgE Profil
Das ALEX IgE-Profil ermöglicht die Messung der IgE-Antikörper (Immunoglobulin E) im Blut, die eine wichtige Rolle bei allergischen Reaktionen spielen. In diesem Screening wird spezifisches IgE gegen knapp 300 Allergieauslöser bestimmt.
100,00 € 3.265,00 €
Toxische Metall­belastung
Bei der Diagnostik toxischer Metalle im Blut wird der Gehalt an bestimmten Metallen im Blut gemessen und festzustellen, ob eine übermäßige Belastung mit giftigen Metallen vorliegt. Die Exposition gegenüber toxischen Metallen kann aus verschiedenen Quellen stammen, darunter Umweltverschmutzung, Arbeitsplatzexposition, Medikamente oder Nahrungsmittel.
124,85 €
[P] Profil Vitamin D
803,00 €
Carona new product
WHO works to ensure that policies and standards are in place to improve access to a broad range of health products for COVID-19 including medicines, vaccines, medical devices, and in vitro diagnostics. In addition, WHO works to ensure that health products such as assistive technology, remain available during pandemic situations. WHO produces guidance on standards to facilitate the development, production, validation and assessment of health products. WHO also supports the selection of COVID-19 health products for procurement through development of technical specifications and priority essential lists.
3.000,00 €
Allergyn­door allergens
1.000,00 €
Cortisol Awakening Response (CAR)
Der Cortisolspiegel beim Erwachen folgt normalerweise einem bestimmten Verlauf. Dieser Verlauf korrelliert mit der Nebennierenfunktion und der sog. HPA- oder Stressachse des VNS.
69,35 €
test product Amazon
Bursting with imagery, motion, interaction and distraction though it is, today’s World Wide Web is still primarily a conduit for textual information. In HTML5, the focus on writing and authorship is more pronounced than ever. It’s evident in the very way that new elements such as article and aside are named. HTML5 asks us to treat the HTML document more as… well, a document. It’s not just the specifications that are changing, either. Much has been made of permutations to Google’s algorithms, which are beginning to favor better written, more authoritative content (and making work for the growing content strategy industry). Google’s bots are now charged with asking questions like, “Was the article edited well, or does it appear sloppy or hastily produced?” and “Does this article provide a complete or comprehensive description of the topic?,” the sorts of questions one might expect to be posed by an earnest college professor. This increased support for quality writing, allied with the book-like convenience and tactility of smartphones and tablets, means there has never been a better time for reading online. The remaining task is to make the writing itself a joy to read. What Is The Perfect Paragraph? # As designers, we are frequently and incorrectly reminded that our job is to “make things pretty.” We are indeed designers — not artists — and there is no place for formalism in good design. Web design has a function, and that function is to communicate the message for which the Web page was conceived. The medium is not the message. Never is this principle more pertinent than when dealing with type, the bread and butter of Web-borne communication. A well-set paragraph of text is not supposed to wow the reader; the wowing should be left to the idea or observation for which the paragraph is a vehicle. In fact, the perfect paragraph is unassuming to the point of near invisibility. That is not to say that the appearance of your text should have no appeal at all. On the contrary: well-balanced, comfortably read typography is a thing of beauty; it’s just not the arresting sort of beauty that might distract you from reading.
1.500,00 € 1.000,00 €
New product
2.500,00 € 2.000,00 €
Allergy demo product
Allergies occur when your immune system reacts to a foreign substance — such as pollen, bee venom or pet dander — or a food that doesn't cause a reaction in most people. Your immune system produces substances known as antibodies
150,00 €
product Testing system test
product Testing system test product Testing system testproduct Testing system testproduct Testing system test
500,00 € 1.000,00 €